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Can a suture coating fight infection after wisdom tooth surgery?

NCT ID NCT07794280

Disease control Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether sutures coated with chlorhexidine, an antibacterial agent, improve healing after impacted wisdom tooth removal. Researchers will compare coated sutures with standard uncoated sutures in the same person, using a split-mouth design where one extraction site gets each type. They will measure bacterial levels and soft tissue healing at days 3, 5, and 7 after surgery. The goal is to see if the coated sutures reduce bacteria and promote better healing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chlorhexidine diacetate-coated polyglactin 910 sutures
What this could lead to
If it works, this could point toward a simple way to lower infection risk and speed up healing after wisdom tooth surgery.
What could go wrong
This is a small early trial with only 20 participants, so results may not apply broadly. The coated sutures might not reduce bacteria enough to make a real difference in healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 to 35 years * Patients indicated for surgical removal of an impacted mandibular (lower) third molar * Patients with two symmetrical impacted mandibular third molars of the same difficulty level according to the Pell-Gregory classification, with a difference in the angulation of the tooth axis (Winter classification) between the two teeth not exceeding 15 degrees Exclusion Criteria: * Patients whose adjacent mandibular second molar is severely decayed/broken down, has only a residual root, or has been extracted * Patients using local or systemic antibiotics within 4 weeks before surgery * Patients using anti-inflammatory drugs or hormonal medications * Patients who are pregnant or breastfeeding * Patients allergic to any component of 2% lidocaine with 1:100,000 epinephrine or to any other medication used in the study * Patients with systemic diseases such as hypertension, diabetes mellitus, blood disorders, or immunodeficiency that may affect the study results * Patients with poor oral hygiene, long-term smoking, or chronic alcohol dependence * Patients with radiographic signs suggesting a tumor or cyst associated with the mandibular third molar

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted third molar tooth Surgical wound healing

How to take part

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