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Can a laser beam speed recovery from heart bypass surgery?

NCT ID NCT07699679

Disease control Sponsor: Federal University of São Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial investigates whether photobiomodulation—applying low-level laser light to the surgical wound—can improve healing and reduce complications after coronary artery bypass grafting (CABG). It compares two methods of harvesting the saphenous vein (the conventional technique and the no-touch technique) in 292 heart disease patients. The study measures wound healing, functional capacity, and overall recovery. If successful, this approach could offer a simple, non-drug way to enhance postoperative outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Photobiomodulation therapy (low-level laser light)
What this could lead to
If effective, this light therapy could speed wound healing and reduce complications after heart bypass surgery, improving recovery.
What could go wrong
This is a mid-sized trial testing a device, not a drug. The effect may be small or no better than placebo, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 292 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG) * Use of the saphenous vein as a graft for myocardial revascularization * Ability to understand the study procedures and provide written informed consent Exclusion Criteria: * Emergency coronary artery bypass surgery * Previous surgery in the lower limb that prevents saphenous vein harvesting * Active infection at the surgical site or lower limb * Severe peripheral arterial disease in the lower limbs * Hemodynamic instability preventing study protocol procedures * Participation in another interventional clinical trial that may interfere with the outcomes of this study * Patients unable to perform postoperative functional capacity assessments * Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery bypass graft (CABG) Coronary artery disease Surgical wound healing

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital São Paulo, Federal University of São Paulo

    São Paulo, São Paulo, 04021001, Brazil

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