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Can botox help surgical wounds heal better?

NCT ID NCT07795463

Symptom relief Sponsor: Pham Ngoc Thach University of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether injecting botulinum toxin type A (Botox) along the surgical incision can improve wound healing and scar appearance after laparoscopic colectomy, a type of colon surgery. Half of the participants receive the injections right after wound closure, while the other half receive standard wound care without the injections. Researchers then compare wound healing scores and scar quality during follow-up visits, and monitor for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Botulinum toxin type A (Botox) injected along the surgical incision
What this could lead to
If it works, this could offer a simple way to improve wound healing and reduce scarring after abdominal surgery.
What could go wrong
This is a small, early-stage trial, and the results may not apply to all patients. Botulinum toxin can cause temporary muscle weakness or allergic reactions, and its effect on wound healing is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older. * Vietnamese nationality. * Indication for laparoscopic colectomy. * Willing and able to provide written informed consent to participate in the study. Exclusion Criteria: * Pregnancy or breastfeeding. * History of allergy to botulinum toxin type A. * History of botulinum toxin type A injection at or near the surgical site within the previous 6 months. * History of radiotherapy, chemotherapy, hematologic disorders, psychiatric disorders, or myasthenia gravis. * Unstable chronic diseases, including uncontrolled hypertension or diabetes mellitus. * Unable to attend scheduled follow-up visits.

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Conditions

The condition(s) this trial relates to.

Surgical Wound

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Botulinum toxin, type A Surgical wound healing

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Thong Nhat hospital

    RECRUITING

    Ho Chi Minh City, Vietnam

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