New hope for kids with leukemia: smarter treatment aims for higher cure rates

NCT ID NCT03020030

First seen Jan 27, 2026 · Last updated Jun 16, 2026 · Updated 23 times

Summary

This study looks at a better way to treat children and teens newly diagnosed with acute lymphoblastic leukemia (ALL), a blood cancer. It uses updated risk factors to decide how strong the chemotherapy should be and tests a new method for dosing a key drug called pegaspargase. The goal is to improve the chance of cure while reducing side effects. About 560 participants are involved in this phase 3 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Centre Hospitalier U. de Quebec

    Québec, Quebec, Canada

  • Columbia University Medical Center, Morgan Stanley Children's Hospital of New York-Presbyterian

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Hasbro Children's Hospital / Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Hospital Sainte Justine, University of Montreal

    Montreal, Quebec, Canada

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.