New combo shows promise against tough lymphoma
NCT ID NCT03113500
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests a new combination treatment for a rare type of lymphoma (CD30-positive peripheral T-cell lymphoma). It combines a targeted drug (brentuximab vedotin) with standard chemotherapy. The goal is to see if this approach improves the number of patients who achieve complete remission. The study enrolled 48 adults and is no longer recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
brentuximab vedotin plus chemotherapy (cyclophosphamide, doxorubicin, etoposide, prednisone)
What this could lead to
If successful, this combination could offer a more effective first-line treatment for CD30-positive peripheral T-cell lymphoma, potentially leading to higher remission rates.
What could go wrong
This is a small, early-phase (Phase 2) study with only 48 participants. Results may not apply to all patients, and side effects from the chemotherapy and targeted drug could be significant.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6, Canada
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States