New study aims to predict chemo risks for seniors with breast cancer

NCT ID NCT01472094

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for ways to predict which older adults (age 65 and up) with early-stage breast cancer are more likely to have serious side effects from chemotherapy. Researchers will collect medical information and blood samples from 700 participants to build a model that could help doctors tailor treatments. The goal is to reduce harm and improve quality of life for older cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors predict which older adults are at higher risk for chemotherapy side effects, allowing for safer, more personalized treatment plans.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and the findings might not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Hofstra-North-LIJ Cancer Institute

    New Hyde Park, New York, 11042, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22903, United States

  • Wake Forest University

    Winston-Salem, North Carolina, 27106, United States

  • Washington University St. Louis

    St Louis, Missouri, 63110, United States

  • Yale University

    New Haven, Connecticut, 06510, United States