New drug combo shows promise in slowing advanced breast cancer

NCT ID NCT03568422

First seen Mar 28, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests a new drug called CFI-402257 combined with a standard chemotherapy (paclitaxel) in people with advanced HER2-negative breast cancer that cannot be cured. The goal is to find the safest dose and see if the combination shrinks tumors better than chemo alone. About 37 women will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • BCCA - Vancouver Cancer Centre

    Vancouver, British Columbia, V5Z 4E6, Canada

  • Kingston Health Sciences Centre

    Kingston, Ontario, K7L 2V7, Canada

  • Ottawa Hospital Research Institute

    Ottawa, Ontario, K1H 8L6, Canada

  • University Health Network

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.