Can a virus tip the balance? unraveling lung bacteria in cystic fibrosis

NCT ID NCT06188988

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates how viral infections influence the community of bacteria in the airways of young children with cystic fibrosis. Researchers will collect throat swabs from children under 5 years old over one year, tracking their microbiome, inflammation, and clinical symptoms. The goal is to understand why viral infections can lead to more harmful bacteria and worsen lung disease, potentially guiding future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal how viral infections worsen lung damage in cystic fibrosis, pointing toward new ways to prevent or treat respiratory complications in young children.
What could go wrong
This is a small observational study, so findings may not apply broadly. It aims to understand mechanisms, not test a treatment, so direct clinical benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Antwerp University Hospital

    Edegem, Antwerp, 2650, Belgium

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