Hidden spinal cord changes may lurk in common neck pain

NCT ID NCT07823426

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First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers at a Turkish hospital are observing 400 adults who visit a pain clinic with cervical radicular pain, the shooting or aching arm pain that comes from a pinched nerve root in the neck. Participants receive routine neurological exams, including the Hoffmann sign, and cervical MRI scans as part of their normal care. The study measures how often MRI reveals signal abnormalities in the spinal cord, including myelomalacia, and records which treatments doctors choose. The study does not assign any treatment or test; it only observes what happens in routine practice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers map how often MRI signal changes appear in people with radiating neck pain, doctors could better judge who needs closer monitoring or earlier surgical referral.
What could go wrong
This is an observational study, so it cannot prove what causes the MRI findings or which treatment works best. Results from one hospital's pain clinic may not apply to other settings.

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Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of 400 consecutive adult patients presenting to the tertiary Pain Medicine Clinic of Ankara Bilkent City Hospital with cervical radicular pain. Participants will be prospectively enrolled during routine clinical evaluation. Clinical and neurological examination findings, cervical MRI characteristics, and the treatment strategy selected by the treating physician will be recorded. No diagnostic or therapeutic intervention will be assigned by the study protocol.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Presentation to the pain clinic with cervical radicular pain * Clinical symptoms and/or examination findings consistent with cervical nerve root involvement * Availability of a cervical magnetic resonance imaging (MRI) examination suitable for evaluation * Completion of standardized neurological examination at the initial visit * Ability and willingness to provide written informed consent Exclusion Criteria: * Previous cervical spine surgery * Acute cervical spine trauma * Known cervical spinal malignancy * Active spinal infection * Known inflammatory, demyelinating, or other non-degenerative spinal cord disease * Severe cognitive impairment or communication difficulty preventing reliable clinical assessment * Inadequate or non-diagnostic cervical MRI quality * Refusal to participate

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Conditions

The condition(s) this trial relates to.

radiculopathy Spinal Cord Compression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, 06680, Turkey (Türkiye)

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