Brain scan and spinal tap study aims to speed up ataxia drug trials

NCT ID NCT04288128

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 40 people with spinocerebellar ataxia types 2 and 7, a rare brain disease that affects movement. Researchers used MRI scans and lumbar punctures over one year to track changes in the brain and body. The goal was to find reliable markers that could be used in future trials of experimental gene-targeting drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could identify reliable markers to speed up testing of new treatments for spinocerebellar ataxia.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear markers, and any findings will need confirmation in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut du Cerveau - Paris Brain Institute

    Paris, 75013, France

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