Could zapping the Brain's cerebellum boost cognition in mental illness?

NCT ID NCT03217110

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) applied to the cerebellum can improve cognitive deficits and mood in people with schizophrenia, autism, bipolar disorder, depression, or Parkinson's disease. Researchers will compare real stimulation to sham (fake) stimulation in 200 participants. The goal is to see if this approach can help with thinking skills and emotional symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS)

What this could lead to

If it works, this could point toward a non-invasive brain stimulation treatment for cognitive problems in several mental health and neurological conditions.

What could go wrong

This is an early-stage study with no phase, so results are uncertain. The effect may be small or not last, and risks like seizures or discomfort are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder bipolar disorder Depression depressive disorder major depressive disorder Parkinson disease schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••