Can a simple cream soothe diabetic dry feet?
NCT ID NCT00947726
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a ceramide-based foot cream (CeraVe) applied twice daily for two weeks could reduce water loss and dryness in the feet of people with non-insulin dependent diabetes. Ten adults with moderate to severe dry feet participated. The goal was to see if the cream could improve skin hydration and comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ceramide-based foot cream (CeraVe)
- What this could lead to
- If it works, this could offer a simple over-the-counter cream to help people with diabetes manage dry, cracked feet.
- What could go wrong
- This was a very small trial with only 10 people and no control group, so results may not apply widely. The cream may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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10 people
The number who actually took part.
- Start date
-
Jul 2009
- Finished
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Jul 2010
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \>18 years of age * non insulin-dependent diabetes * moderate to severe xerosis of both feet \[a score of at least 4 on a scale of 0 (normal) to 8 (deep fissuring)\] * capable of understanding and signing consent form Exclusion Criteria: * history of ichthyosis vulgaris * known hypersensitivity to the topical product used in the study * previous use of high potency steroids (class I and II) in past 2 week * presence of acute skin disease or infection, such as vasculitis or cellulitis * presence of foot ulcer * evidence of gangrene
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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