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Shoulder pain study: why some patients may not respond to steroid shots

NCT ID NCT06404125

Completed Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 44 people with shoulder pain from rotator cuff problems to see if their level of central sensitization (a heightened pain response in the nervous system) affected how well a steroid injection worked. Researchers measured pain sensitivity before the injection and then checked outcomes like shoulder movement and grip strength. The goal was to understand why some patients don't respond to this common treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
corticosteroid injection
What this could lead to
If it works, this could help doctors predict which patients with shoulder pain will benefit from steroid injections, leading to more personalized treatment.
What could go wrong
This is a small, completed observational study, not a treatment trial. It only looks at a possible link, so it cannot prove that changing treatment based on central sensitization improves outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome rotator cuff syndrome shoulder impingement syndrome Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN ROTATOR CUFF LESION SHOULDER PAIN SUBACROMIAL IMPINGEMENT SYNDROME

Contacts and locations

Locations

  • Sultan 2. Abdulhamid Han Training and Research Hospital

    Istanbul, Üsküdar, 34674, Turkey (Türkiye)

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