New antibiotic combo tested in healthy volunteers
NCT ID NCT06665555
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study tested how two antibiotics, ceftibuten and ledaborbactam, move through the blood and lungs of 34 healthy adults aged 18-55. Participants took five doses of the drugs and underwent a bronchoscopy to measure drug levels in lung fluid. The goal was to understand safety and drug distribution, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ceftibuten and ledaborbactam etzadroxil
What this could lead to
If successful, this could help determine the right doses for future studies of this antibiotic combination against lung infections.
What could go wrong
This is an early Phase 1 study in healthy volunteers, not patients. It only measures drug levels, not whether the drug works against infections. Results may not predict real-world effectiveness.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Pulmonary Associates
Phoenix, Arizona, 85032, United States