Hunt for CDH genes launches: 3,000 participants sought
NCT ID NCT00950118
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study aims to identify genes that make a person more likely to develop congenital diaphragmatic hernia (CDH), a birth defect where the diaphragm doesn't form properly. Researchers will collect DNA samples from 3,000 people with CDH or a family history of it, along with their families. By understanding the genetic causes, they hope to pave the way for future prevention or treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could identify genetic risk factors for congenital diaphragmatic hernia, pointing toward future prevention or treatment strategies.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It may take years to translate findings into clinical applications, and the genetic causes may be complex and hard to pinpoint.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo University Hospital
RECRUITINGCairo, Egypt
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Children's Hospital of Omaha/ University of Nebraska
RECRUITINGOmaha, Nebraska, 68114, United States
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Children's Hospital of Pittsburgh/ University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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Cincinnati Children's Hospital and Medical Center/ University of Cincinnati
RECRUITINGCincinnati, Ohio, 45229, United States
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Medical College of Wisconsin
COMPLETEDMilwaukee, Wisconsin, 53226, United States
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Monroe Carrell Jr Children's Hospital at Vanderbilt
COMPLETEDNashville, Tennessee, 37232, United States
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Morgan Stanley Children's Hospital of New York- Presbyterian (Columbia University Medical Center)
RECRUITINGNew York, New York, 10032, United States
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New York University, Hassenfeld Children's Hospital at NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Northwell Health
RECRUITINGManhasset, New York, 11030, United States
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Oregon Health & Science University, Doernbecher Children's Hospital
RECRUITINGPortland, Oregon, 97239, United States
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Rush Hospital
RECRUITINGChicago, Illinois, 60612, United States
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UT Southwestern Medical Center, Children's Health, Dallas
RECRUITINGDallas, Texas, 75235, United States
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University of Michigan/ CS Mott Children's Hospital
RECRUITINGAnn Arbor, Michigan, 48167-5245, United States
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Washington University Medical Center/ St. Louis Children's Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can 3D models bring a Baby's birth defect into focus before birth?
- Can a tiny balloon in the womb save babies born with a hole in their diaphragm?
- Tiny balloon inside womb could help babies breathe
- Teens' sports struggles after rare birth defect surgery: study seeks answers
- New trial could change how doctors help CDH babies at birth
- Pioneering fetal surgery aims to save babies born with a hole in their diaphragm