Hunt for CDH genes launches: 3,000 participants sought

NCT ID NCT00950118

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study aims to identify genes that make a person more likely to develop congenital diaphragmatic hernia (CDH), a birth defect where the diaphragm doesn't form properly. Researchers will collect DNA samples from 3,000 people with CDH or a family history of it, along with their families. By understanding the genetic causes, they hope to pave the way for future prevention or treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could identify genetic risk factors for congenital diaphragmatic hernia, pointing toward future prevention or treatment strategies.

What could go wrong

This is an observational genetic study, not a treatment trial. It may take years to translate findings into clinical applications, and the genetic causes may be complex and hard to pinpoint.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital diaphragmatic hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Cairo University Hospital

    RECRUITING

    Cairo, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Children's Hospital of Omaha/ University of Nebraska

    RECRUITING

    Omaha, Nebraska, 68114, United States

    Contact

    Contact Email: •••••@•••••

  • Children's Hospital of Pittsburgh/ University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital and Medical Center/ University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    COMPLETED

    Milwaukee, Wisconsin, 53226, United States

  • Monroe Carrell Jr Children's Hospital at Vanderbilt

    COMPLETED

    Nashville, Tennessee, 37232, United States

  • Morgan Stanley Children's Hospital of New York- Presbyterian (Columbia University Medical Center)

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York University, Hassenfeld Children's Hospital at NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • Northwell Health

    RECRUITING

    Manhasset, New York, 11030, United States

    Contact Email: •••••@•••••

    Contact

  • Oregon Health & Science University, Doernbecher Children's Hospital

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Rush Hospital

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact

  • UT Southwestern Medical Center, Children's Health, Dallas

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan/ CS Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48167-5245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University Medical Center/ St. Louis Children's Hospital

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Email: •••••@•••••