Experimental combo targets relapsed blood cancers after transplant

NCT ID NCT03912064

First seen Sep 30, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This early-phase study tests a new treatment for people whose blood cancer (like AML or MDS) has returned after a donor stem cell transplant. The treatment combines a special type of donor immune cell infusion with an immunotherapy drug (ipilimumab) to help fight the cancer. The main goal is to find the safest dose and understand side effects in about 25 participants.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.