Engineered immune cells target three tough autoimmune diseases

NCT ID NCT06947460

First seen Mar 08, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This study tests a new treatment using a patient's own immune cells, modified to target and destroy harmful cells in three severe autoimmune conditions: lupus nephritis, systemic sclerosis, and Sjogren's syndrome with pulmonary hypertension. About 45 adults will receive a single infusion of these cells, called CD19-BCMA CAR T cells. The main goal is to check safety, especially any serious side effects within the first month, and to see if the treatment can reduce disease activity.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 北京高博医院

    RECRUITING

    Beijing, China,Beijing, 102200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.