AI-Powered pulse check could spot hidden heart defects in newborns

NCT ID NCT05637814

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a machine learning algorithm can better detect critical congenital heart disease (CCHD) in newborns by combining standard oxygen saturation measurements with perfusion index data. Researchers will enroll up to 320 infants, including those with suspected or confirmed heart conditions and healthy babies. The goal is to see if the AI approach improves screening accuracy compared to current methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SpO2/PIx measurement and ML algorithm

What this could lead to

If successful, this could make newborn screening for critical heart defects more accurate, catching more cases early and reducing missed diagnoses.

What could go wrong

This is a validation study, not a treatment trial. The algorithm may not perform better than current screening methods, and results may not apply to all hospitals or populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cohen Children's Medical Center

    NOT_YET_RECRUITING

    Queens, New York, 11040, United States

    Contact Email: •••••@•••••

    Contact

  • UC Davis Medical Center

    RECRUITING

    Davis, California, 95616, United States

    Contact Email: •••••@•••••

    Contact

  • University of Utah Health Care

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84102, United States

    Contact Email: •••••@•••••

    Contact