New drug targets DNA in Hard-to-Treat cancers
NCT ID NCT05691517
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times
Summary
This early-stage trial tests CBX-12, a drug that damages cancer cell DNA to kill them, in about 35 adults with advanced or metastatic solid tumors that have worsened after at least one prior treatment. The main goal is to see how the drug affects DNA repair in tumors. This is not a cure, but aims to control the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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National Cancer Institute Developmental Therapeutics Clinic
RECRUITINGBethesda, Maryland, 20892, United States
Contact
Contact Phone: •••-•••-••••
Conditions
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