CBD boosts talk therapy for anxiety? new trial investigates
NCT ID NCT07123467
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing whether adding a low or moderate dose of FDA-approved cannabidiol (Epidiolex) to cognitive behavioral therapy (CBT) helps adults with generalized anxiety disorder more than CBT plus a placebo. Researchers will measure changes in brain activity related to emotion regulation and anxiety symptoms. The trial enrolls 90 adults aged 18-45 who are generally healthy and have a current GAD diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cannabidiol (Epidiolex)
What this could lead to
If successful, this could point toward a new way to boost the effects of talk therapy for anxiety, potentially helping people feel better faster or with fewer sessions.
What could go wrong
This is still an early-stage Phase 3 trial with only 90 participants, so results may not apply to everyone. The improvement in brain activity measured by fMRI may not translate to noticeable real-world benefits.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Wayne State University School of Medicine, Tolan Park Medical Building
RECRUITINGDetroit, Michigan, 48201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact