CBD boosts talk therapy for anxiety? new trial investigates
NCT ID NCT07123467
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing whether adding a low or moderate dose of FDA-approved cannabidiol (Epidiolex) to cognitive behavioral therapy (CBT) helps adults with generalized anxiety disorder more than CBT plus a placebo. Researchers will measure changes in brain activity related to emotion regulation and anxiety symptoms. The trial enrolls 90 adults aged 18-45 who are generally healthy and have a current GAD diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cannabidiol (Epidiolex)
- What this could lead to
- If successful, this could point toward a new way to boost the effects of talk therapy for anxiety, potentially helping people feel better faster or with fewer sessions.
- What could go wrong
- This is still an early-stage Phase 3 trial with only 90 participants, so results may not apply to everyone. The improvement in brain activity measured by fMRI may not translate to noticeable real-world benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Wayne State University School of Medicine, Tolan Park Medical Building
RECRUITINGDetroit, Michigan, 48201, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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