Engineered immune cells take on deadly brain cancer

NCT ID NCT05660369

First seen Nov 20, 2025 · Last updated May 20, 2026 · Updated 24 times

Summary

This early-phase study tests a new treatment called CARv3-TEAM-E T cells for people with glioblastoma, a fast-growing brain cancer. The treatment uses the patient's own immune cells, modified in a lab to better recognize and attack the tumor. The main goal is to find the safest dose and understand side effects in up to 21 participants whose cancer has returned.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital Cancer Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.