Promising drug cocktail may stall smoldering myeloma

NCT ID NCT01572480

First seen Mar 20, 2026 · Last updated May 09, 2026 · Updated 11 times

Summary

This study tested a combination of three drugs (carfilzomib, lenalidomide, and dexamethasone) in 55 people with high-risk smoldering multiple myeloma, a condition that often leads to active myeloma. The goal was to see if early treatment could reduce or eliminate cancer cells in the bone marrow. Participants received eight cycles of the three drugs, followed by up to 12 cycles of lenalidomide alone if their disease did not worsen.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.