New four-drug cocktail shows promise for hard-to-treat multiple myeloma

NCT ID NCT01297764

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 23 times

Summary

This early-phase study tested a combination of four drugs (carfilzomib, lenalidomide, vorinostat, and dexamethasone) in 17 people with multiple myeloma that had come back or stopped responding to at least one prior treatment. The main goals were to find a safe dose and see how well the drugs work together. The study is no longer recruiting, and results will help guide future treatment options for this blood cancer.

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Contacts and locations

Locations

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

Conditions

Explore the condition pages connected to this study.