Chest pain study: could a quick outpatient visit replace hospitalization?

NCT ID NCT05897632

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a rapid outpatient evaluation within 72 hours of an emergency department visit is as safe and effective as hospitalization for people with chest pain at moderate risk of a heart attack. About 500 participants will be randomly assigned to either outpatient care or hospital admission. The goal is to see which approach leads to fewer days spent in the hospital over the next month and year, while keeping patients safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that rapid outpatient evaluation is as safe as hospitalization for moderate-risk chest pain, reducing hospital stays and healthcare costs.

What could go wrong

This is a behavioral study, not testing a new drug or device. Results may not apply to all chest pain patients, and the outpatient approach might miss some heart issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome cardiovascular disorder Chest Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Carolinas Medical Center

    RECRUITING

    Charlotte, North Carolina, 28203, United States

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Wake Forest University Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Email: •••••@•••••