Chest pain study: could a quick outpatient visit replace hospitalization?

NCT ID NCT05897632

Recruiting now Knowledge-focused Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a rapid outpatient evaluation within 72 hours of an emergency department visit is as safe and effective as hospitalization for people with chest pain at moderate risk of a heart attack. About 500 participants will be randomly assigned to either outpatient care or hospital admission. The goal is to see which approach leads to fewer days spent in the hospital over the next month and year, while keeping patients safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that rapid outpatient evaluation is as safe as hospitalization for moderate-risk chest pain, reducing hospital stays and healthcare costs.
What could go wrong: This is a behavioral study, not testing a new drug or device. Results may not apply to all chest pain patients, and the outpatient approach might miss some heart issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome cardiovascular disorder Chest Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEST PAIN

Contacts and locations

Locations

Carolinas Medical Center
RECRUITING

Charlotte, North Carolina, 28203, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Wake Forest University Health Sciences
RECRUITING

Winston-Salem, North Carolina, 27157, United States

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