New hope for heart lining pain: can CardiolRx keep flare-ups away?

NCT ID NCT06708299

Recruiting now Disease control Sponsor: Cardiol Therapeutics Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study tests whether the drug CardiolRx can prevent another episode of pericarditis (inflammation around the heart) in people who have had repeated attacks. About 110 adults who have been stable on an IL-1 blocker for at least a year will stop that medication and receive either CardiolRx or a placebo for 24 weeks. The goal is to see if CardiolRx helps them stay free of recurrence.

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Conditions

The condition(s) this trial relates to.

idiopathic recurrent pericarditis pericarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECURRENT PERICARDITIS

Contacts and locations

Locations

Altman Clinical and Translational Research Institute
RECRUITING

La Jolla, California, 92037, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Columbia University - New York Presbyterian
RECRUITING

New York, New York, 10032, United States
Fatebenefratelli Hospital Milano
NOT_YET_RECRUITING

Milan, Italy
Hippokration General Hospital
RECRUITING

Athens, Greece
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Jewish General Hospital
RECRUITING

Montreal, Canada
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21205, United States
Lenox Hill Hospital
RECRUITING

New York, New York, 11030, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clionic Arizona
RECRUITING

Phoenix, Arizona, 85054, United States
MedStar Health Institute
RECRUITING

Columbia, Maryland, 21044, United States
Minneapolis Heart Institute
RECRUITING

Minneapolis, Minnesota, 55407, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60208, United States
Pacific Heart Institute at Cedars-Sinai
RECRUITING

Santa Monica, California, 90404, United States
UCI Health
RECRUITING

Irvine, California, 92697, United States
University Hospital
NOT_YET_RECRUITING

Torino, Italy
University Hospital Udine
NOT_YET_RECRUITING

Udine, Italy
University of Padua
NOT_YET_RECRUITING

Padua, Italy
University of Utah Hospital
RECRUITING

Salt Lake City, Utah, 84112, United States
University of Vermont
RECRUITING

Burlington, Vermont, 05401, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States
Virginia Commonwealth University
RECRUITING

Richmond, Virginia, 23219, United States

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