CBD drug shows promise for stubborn chest pain in heart inflammation study

NCT ID NCT05494788

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study tested a pure cannabidiol (CBD) drug called CardiolRx in 27 adults with recurrent pericarditis, a condition where the heart's lining becomes inflamed and causes chest pain. The goal was to see if the drug is safe and can help reduce pain and inflammation, while also allowing patients to lower their use of steroids. Results focused on pain scores and inflammation markers over 8 weeks.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MedStar Health Research Institute

    Washington D.C., District of Columbia, 20010, United States

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407, United States

  • Pima Heart and Vascular Clinical Research

    Tucson, Arizona, 85719, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Virginia Commonwealth University Health

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.