Heart risks after CAR-T? new study investigates

NCT ID NCT06350994

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 43 times

Summary

This study looks at whether CAR-T cell therapy, a new immune treatment for blood cancers, can cause early heart problems. Researchers will check heart function with ultrasound in 60 patients before and a few days after treatment. The goal is to find out how often heart issues happen and what they look like.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Critical care medicine department

    RECRUITING

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR-T cells

What this could lead to

If it works, this could help doctors understand and monitor heart risks after CAR-T therapy.

What could go wrong

This is a small, early observational study, not a treatment trial. It may not find clear links or change practice.

Conditions

The condition(s) this trial relates to.

B-cell neoplasm cardiomyopathy Cardiotoxicity hematopoietic and lymphoid system neoplasm plasma cell myeloma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.