New radiation approach targets inoperable pancreatic tumors

NCT ID NCT03403049

Completed Disease control Sponsor: Montefiore Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a new type of radiation called carbon ion therapy for people with locally advanced pancreatic cancer that cannot be removed by surgery. Fourteen participants received increasing doses of carbon ion radiation along with chemotherapy. The main goal was to find the highest safe dose that doesn't cause severe side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: carbon ion radiation therapy
What this could lead to: If successful, this could establish a safer radiation dose for treating inoperable pancreatic cancer, potentially improving tumor control.
What could go wrong: This is a very early, small Phase I trial with only 14 participants, focused on safety, not effectiveness. The treatment may still cause severe side effects or fail to shrink tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer malignant pancreatic neoplasm neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER PANCREATIC CANCER

Contacts and locations

Locations

Albert Einstein College of Medicine

The Bronx, New York, 10461, United States
Shanghai Proton and Heavy Ion Center

Shanghai, Shanghai Municipality, China

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