Revolutionary immune cell therapy battles aggressive blood cancer Head-On

NCT ID NCT05605899

Recruiting now Disease control Sponsor: Kite, A Gilead Company Source: ClinicalTrials.gov ↗

Summary

This study compares a personalized immune cell therapy (CAR-T) against standard chemotherapy as the first treatment for people with high-risk, aggressive lymphoma. The trial will enroll 300 participants who have just started treatment to see if CAR-T therapy can better control the cancer and improve survival. Researchers will track how long patients live without their cancer worsening and monitor side effects over many years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ASST Degli Spedali Civili di Brescia
RECRUITING

Brescia, 25123, Italy
Academisch Medisch Centrum
RECRUITING

Amsterdam, 1081HV, Netherlands
Addenbrookes Hospital (Cambridge University Hospitals NHS Foundation Trust)
RECRUITING

Birmingham, B15 2TH, United Kingdom
Avera Cancer Institute
WITHDRAWN

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia
RECRUITING

Perugia, 06132, Italy
Banner MD Anderson Cancer Center
RECRUITING

Gilbert, Arizona, 85234, United States
CHU Bordeaux-Hopital Haut-Leveque
RECRUITING

Bordeaux, France
CHU Dijon
RECRUITING

Dijon, 21079, France
CHU Pontchaillou
RECRUITING

Rennes, 35033, France
Centre Hospitalier Universitaire de Nice
RECRUITING

Nice, CS 23079, France
Centre Hospitalier Universitaire(CHU) de Toulouse
RECRUITING

Toulouse, 31100, France
Centre Leon Berard
RECRUITING

Cedex Lyon 08, 69008, France
Centro Hospitalar Universitario Lisboa Norte, E.P.E. - Hospital de Santa Maria
RECRUITING

Lisbon, Portugal
Charite Universitaetsmedizin Berlin
RECRUITING

Berlin, Germany
Colorado Blood Cancer Institute
RECRUITING

Denver, Colorado, 80218, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Fred Hutchinson Cancer Center
WITHDRAWN

Seattle, Washington, 98109, United States
Georgia Cancer Center at Augusta University
RECRUITING

Augusta, Georgia, 30912, United States
Grande Ospedale Metropolitano Bianchi Melacrino Morelli
RECRUITING

Reggio Calabria, 89133, Italy
Helios Klinikum Berlin-Buch
RECRUITING

Berlin, 13125, Germany
Henry-Joyce Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States
Hopital Claude Huriez CHU Lille, Service Maladies du sang
RECRUITING

Lille, 59037, France
Hopital Henri MONDOR, APHP
RECRUITING

Paris, 94000, France
Hopital Saint Eloi
RECRUITING

Montpellier, 34295, France
Hospital Clínico Universitario de Valencia
RECRUITING

Valencia, 46010, Spain
Hospital Universitari Vall D'Hebron
RECRUITING

Barcelona, 8035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Marqués de Valdecilla
RECRUITING

Santander, 39008, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitario de Salamanca
RECRUITING

Salamanca, 37007, Spain
IRCCS Azienda Ospedaliero-Universitaria di Bologna
RECRUITING

Bologna, 40138, Italy
IRCCS Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
Institut Catala d'Oncologia
RECRUITING

Barcelona, 08908, Spain
Instituto Portugues de Oncologia de Lisboa Francisco Gentil - E.P.E.
RECRUITING

Lisbon, Portugal
Instituto Portugues de Oncologia do Porto Francisco Gentil, E.P.E.
RECRUITING

Porto, 4200-072, Portugal
Intermountain LDS Hospital/Blood and Marrow Transplant/ Acute Leukemia Program
RECRUITING

Salt Lake City, Utah, 84143, United States
Jewish General Hospital
RECRUITING

Montreal, H3T1E2, Canada
John Theurer Cancer Center at Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Juntendo University Hospital
RECRUITING

Tokyo, 113-8431, Japan
Leiden University Medical Center
RECRUITING

Leiden, 2333 ZA, Netherlands
Maastricht Universitair Medisch Centrum
RECRUITING

Maastricht, 62002, Netherlands
Mayo Clinic
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic Cancer Center Outpatient Pharmacy
RECRUITING

Rochester, Minnesota, 55902, United States
Medizinische Universität Innsbruck
RECRUITING

Innsbruck, 6020, Austria
Medizinische Universität Wien (AKH Wien, Medical University Vienna and General Hospital Vienna)
RECRUITING

Vienna, 01090, Austria
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
Northwestern Memorial Hospital
RECRUITING

Chicago, Illinois, 60612, United States
Norton Cancer Institute, St. Matthews Campus
RECRUITING

Shelbyville, Kentucky, 40065, United States
Novant Health Cancer Institute- Hematology
RECRUITING

Charlotte, North Carolina, 28204, United States
Ochsner Clinic Foundation
RECRUITING

New Orleans, Louisiana, 70121, United States
Oncology Hematology Care Clinical Trials, LLC
WITHDRAWN

Cincinnati, Ohio, 45242, United States
Osaka University Hospital
RECRUITING

Osaka, 565-0871, Japan
Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
Peter MacCallum Cancer Center
RECRUITING

Melbourne, Victoria, 3000, Australia
Princess Margaret Cancer Centre
RECRUITING

Toronto, M5G 2M9, Canada
Prisma Health Cancer Institute
RECRUITING

Greenville, South Carolina, 29615, United States
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14203, United States
Royal Brisbane and Women's Hospital
RECRUITING

South Brisbane, Queensland, 4101, Australia
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94305, United States
Tennessee Oncology, PLLC
RECRUITING

Nashville, Tennessee, 37203, United States
The Ottowa Hospital- General Campus
RECRUITING

Ottawa, K1H 8L6, Canada
The University of Kansas Hospital
RECRUITING

Westwood, Kansas, 66205, United States
The University of Texas, MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Tohoku University Hospital
RECRUITING

Miyagi, 980-8574, Japan
Tokyo Metropolitan Komagome Hospital
RECRUITING

Tokyo, 113-8677, Japan
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
UPMC Hillman Cancer Center
WITHDRAWN

Pittsburgh, Pennsylvania, 15232, United States
Uniklinikum Duesseldorf, Klinik fuer Haematologie, Onkologie und klinische Immunologie
RECRUITING

Düsseldorf, 40225, Germany
Universita Cattolica del Sacro Cuore
RECRUITING

Rome, Italy
Universitair Medisch Centrum Utrecht
RECRUITING

Utrecht, 3508 GA, Netherlands
University Hospital, Kyoto Prefectural University of Medicine
RECRUITING

Kyoto, 602-8566,, Japan
University Hospitals Southampton
RECRUITING

Southampton, SO16 6YD, United Kingdom
University Medical Center Groningen
RECRUITING

Groningen, 9700 RB, Netherlands
University of Alabama Hospital
RECRUITING

Birmingham, Alabama, 35233, United States
University of California Los Angeles (UCLA)
RECRUITING

Los Angeles, California, 90095, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
University of MD Greenebaum Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21201, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Rochester Medical Center
RECRUITING

Rochester, New York, 14642, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75235, United States
Universitätsklinik Erlangen
RECRUITING

Erlangen, Germany
Universitätsklinikum St. Pölten
RECRUITING

Sankt Pölten, 3100, Austria
Universitätsklinikum bonn, medizinische klinik III
RECRUITING

Bonn, 53127, Germany
Virginia Commonwealth University
COMPLETED

Richmond, Virginia, 23298, United States
Weill Cornell Medical College - NewYork Presbyterian Hospital
RECRUITING

New York, New York, 10021, United States
Zuniklinikum Salzburg, Landeskrankenhaus, Universitatsklinik fur Innere Medizin III der PMU
RECRUITING

Salzburg, 5020, Austria

Conditions

Explore the condition pages connected to this study.

HIGH-RISK LARGE B-CELL LYMPHOMA (LBCL)