Engineered immune cells take aim at childhood leukemia

NCT ID NCT02650414

First seen Jan 07, 2026 · Last updated May 17, 2026 · Updated 15 times

Summary

This study tests a single dose of specially engineered immune cells (CAR T-cells) in children and young adults with B-cell leukemia that has come back or not responded to standard treatments. The cells are designed to target a protein called CD22 on leukemia cells. The main goal is to see if this approach is safe and possible, and to monitor side effects like cytokine release syndrome.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.