Experimental CAR T-Cell therapy targets tough blood cancers

NCT ID NCT03938987

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized cell therapy called CAR T-cells for people with relapsed or hard-to-treat lymphoma or acute lymphoblastic leukemia (ALL). The therapy involves collecting a patient's own immune cells, modifying them to recognize and attack cancer cells, and infusing them back. The trial aims to find the best dose and evaluate safety and effectiveness in 63 participants aged 2 to 70.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR T-cells (a type of immune cell therapy)

What this could lead to

If successful, this could offer a new treatment option for people with hard-to-treat lymphoma or leukemia.

What could go wrong

This is an early-phase trial with only 63 participants, so results may not apply to everyone. Side effects can be serious, including immune reactions and nerve problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia adult acute lymphoblastic leukemia aggressive B-cell non-Hodgkin lymphoma childhood acute lymphoblastic leukemia non-Hodgkin lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alberta Children's Hospital

    NOT_YET_RECRUITING

    Calgary, Alberta, T3B6A8, Canada

    Contact

  • Cross Cancer Institute

    RECRUITING

    Edmonton, Alberta, T6G1Z2, Canada

    Contact

  • Foothills Medical Centre

    NOT_YET_RECRUITING

    Calgary, Alberta, T2N2T9, Canada

    Contact

  • Stollery Children's Hospital

    NOT_YET_RECRUITING

    Edmonton, Alberta, T6G2B7, Canada

    Contact

  • Tom Baker Cancer Centre

    NOT_YET_RECRUITING

    Calgary, Alberta, T2N4N2, Canada

    Contact

  • University of Alberta Hospital

    RECRUITING

    Edmonton, Alberta, T6G2B7, Canada

    Contact