Engineered immune cells injected into brain fluid show promise against deadly glioblastoma
NCT ID NCT05366179
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 25 times
Summary
This early-phase study tests the safety of a new treatment for glioblastoma, an aggressive brain cancer that has returned or not responded to standard therapy. The treatment involves taking a patient's own immune cells (T cells), modifying them in a lab to recognize and attack cancer cells, and then infusing them directly into the fluid around the brain. The study will enroll 36 adults and primarily aims to identify side effects and the best dose, not to cure the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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