Scientists build a biobank to crack the mystery of CAR-T cell failure

This study collects extra blood and bone marrow samples from people receiving CAR-T cell therapy for lymphoma or acute lymphoblastic leukemia. The goal is to build a biobank that researchers can use to investigate why about half of patients do not respond to this treatment. Participants will give samples at specific times during their treatment journey, including during apheresis, at reinfusion, and during follow-up. No new treatments are being tested; the focus is on gathering biological material for future research.