New immune cell therapy takes on tough pancreatic cancer

NCT ID NCT07553793

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests a new type of cell therapy for people with advanced pancreatic cancer that has stopped responding to chemotherapy. The treatment uses a patient's own immune cells, called macrophages, that are engineered in a lab to recognize and attack cancer cells carrying a protein called C-MET. The study will enroll 18 participants to check the safety of the treatment and see if it can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
CAR-M-C-MET cells (engineered immune cells)
What this could lead to
If this works, it could offer a new treatment option for advanced pancreatic cancer patients who have run out of standard therapies.
What could go wrong
This is a very early phase 1 trial with only 18 participants, so it is not yet clear if the treatment is safe or effective. There is a risk of serious side effects like cytokine release syndrome.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.