New immune cell therapy takes on tough pancreatic cancer
NCT ID NCT07553793
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This early-stage trial tests a new type of cell therapy for people with advanced pancreatic cancer that has stopped responding to chemotherapy. The treatment uses a patient's own immune cells, called macrophages, that are engineered in a lab to recognize and attack cancer cells carrying a protein called C-MET. The study will enroll 18 participants to check the safety of the treatment and see if it can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- CAR-M-C-MET cells (engineered immune cells)
- What this could lead to
- If this works, it could offer a new treatment option for advanced pancreatic cancer patients who have run out of standard therapies.
- What could go wrong
- This is a very early phase 1 trial with only 18 participants, so it is not yet clear if the treatment is safe or effective. There is a risk of serious side effects like cytokine release syndrome.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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