Experimental cell therapy targets scar tissue in failing hearts

NCT ID NCT06902896

First seen Feb 20, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This early-phase study tested a new treatment called CAR-DC in 8 adults with end-stage dilated cardiomyopathy, a condition where the heart becomes enlarged and weak. The therapy uses specially engineered immune cells to target a protein (FAP) linked to scar tissue in the heart. The main goals were to check safety and side effects, while also measuring any changes in heart function.

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Contacts and locations

Locations

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310009, China

Conditions

Explore the condition pages connected to this study.