Could a simple pill before surgery beat back head and neck cancer?
NCT ID NCT07254962
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking a short course of capecitabine pills before surgery can shrink tumors and improve outcomes for people with HPV-negative head and neck cancer. About 75 adults with stage III or IVa cancer will be randomly assigned to either standard care or capecitabine before surgery. The goal is to see if this approach reduces tumor size, makes surgery less complex, and improves cancer-free survival.
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