A drop of blood may reveal hidden fluid leaks in sepsis
NCT ID NCT07733206
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This pilot study tests whether a new index, based on changes in hemoglobin levels after a standard fluid infusion, can measure capillary leak in people with septic shock. Researchers will compare this index to known markers of blood vessel damage in 100 ICU patients. If it works, the index could offer a simple, bedside tool to guide fluid therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- standardised fluid bolus of Ringer's lactate
- What this could lead to
- If validated, this simple index could help doctors tailor fluid therapy for septic shock patients, reducing complications from too much or too little fluid.
- What could go wrong
- This is a small pilot study testing a new formula, not a proven tool. The index may not correlate well with existing biomarkers or improve outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHUM
Fort-de-France, Martinique, 97261, Martinique
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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