Cannabis and HIV: brain health under the microscope

NCT ID NCT05430490

Completed Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how regular cannabis use affects brain health and thinking skills in people with HIV and those without. Researchers used brain scans, blood and spinal fluid tests, and thinking tasks to compare 276 participants. The goal was to understand the combined effects of HIV and cannabis on the brain, which could help guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward ways to protect brain health in people with HIV who use cannabis.
What could go wrong: This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS HIV INFECTIONS

Contacts and locations

Locations

Rutgers University

Newark, New Jersey, 08901, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

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