New hope for hard-to-treat bile duct cancer: combo therapy shows promise

NCT ID NCT05994001

First seen Feb 20, 2026 · Last updated May 15, 2026 · Updated 13 times

Summary

This study tests two drugs, candonilimab and LM-302, in people with advanced biliary tract cancer that has not responded to standard chemotherapy and immunotherapy. The goal is to see if the combination can shrink tumors or slow the disease. About 78 adults with a specific protein (Claudin 18.2) on their cancer cells will take part. This is not a cure, but aims to control the cancer.

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Contacts and locations

Locations

  • Zhongshan hospital, Fudan University

    Shanghai, China

Conditions

Explore the condition pages connected to this study.