New drug targets Cancer's genetic weakness

NCT ID NCT06390865

Summary

This study is testing an oral drug called MLN0128 (TAK-228) in patients with advanced cancers that have stopped responding to other treatments. The drug is specifically for patients whose tumors have certain genetic changes called TSC1 or TSC2 mutations. The goal is to see if blocking specific enzymes can stop or slow cancer growth in these patients.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.