New combo therapy aims to cut blood transfusions in MDS patients
NCT ID NCT04798339
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times
Summary
This early-stage study tests whether adding canakinumab to a standard anemia drug (darbepoetin alfa) can help people with lower-risk myelodysplastic syndromes (MDS) who no longer respond to standard treatment. The goal is to reduce or eliminate the need for blood transfusions. About 13 participants will receive increasing doses to find the safest and most effective dose.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory-Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
Conditions
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