New MRI scan could spot returning head and neck cancer early

NCT ID NCT02862678

Completed Diagnosis Sponsor: CHU de Reims Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special type of MRI (diffusion-weighted MRI) can predict if head and neck cancer will come back after chemoradiotherapy. Fifty-nine patients had two MRIs: one before treatment and one three months after. The goal was to see if changes in water movement in tumors could signal recurrence. If it works, this non-invasive scan might help doctors catch returning cancer sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: diffusion-weighted MRI
What this could lead to: If successful, this MRI technique could help doctors detect early signs of cancer returning after treatment, allowing for faster intervention.
What could go wrong: This is a small pilot study (59 people) with no control group. The MRI's ability to predict recurrence is not yet proven and may not be accurate enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK SQUAMOUS CELL CARCINOMA

Contacts and locations

Locations

Chu de Reims

Reims, 51092, France

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