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Eye test may reveal hidden heart risks

NCT ID NCT03739073

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a non-invasive eye scan (OCTA) can predict how well blood flows in the heart's small arteries. Researchers examined 101 people with coronary artery disease, comparing eye images to measurements taken during heart catheterization. The goal was to see if the eye test could replace or reduce the need for invasive heart procedures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, non-invasive eye test to help assess heart artery health without invasive procedures.
What could go wrong
This is a small, early-stage study (101 participants) focused on finding a correlation, not proving a treatment. The results may not apply to all patients or lead to a reliable test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

101 people

The number who actually took part.

Started

Oct 2018

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male and female patient's ≥18 years of age with coronary arterial indication as usual and with proximal and / or mean IVA stenosis ≥ 50%. 2. Signed informed consent 3. Affiliation to the social security system Exclusion Criteria: 1. Unstable Coronary Artery Disease 2. Atrial fibrillation 3. History of myocardial infarction \<6 months in the territory of the proximal and / or mean IVA. 4. Asthma 5. Aortocoronary bypass surgery. 6. Collateral development at the level of the proximal and / or mean IVA. 7. Allergy to iodine, severe renal insufficiency. 8. Ametropia\> = 6 diopters. 9. History of retinal ocular pathologies other than uncomplicated diabetic retinopathy and hypertensive retinopathy. 10. History of ophthalmic treatments such as macular or panretinal laser photocoagulation, intravitreal injection of anti-VEGF or cortisone. 11. Chronic glaucoma 12. Patients under guardianship or curators. 13. Pregnant or lactating women. 14. Patient's not affiliated to the French social security. 15. Persons placed under the protection of justice, 16. Subject participating in another research including an exclusion period still in progress at pre-inclusion

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease

Contacts and locations

Locations

  • Hospices Civils de Lyon - Hopital de la Croix Rousse

    Lyon, 69004, France

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