Weight-Loss drug semaglutide could be key to treating Obesity-Linked heart failure

NCT ID NCT05371496

ENROLLING_BY_INVITATION Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Mar 17, 2026 · Last updated May 01, 2026 · Updated 7 times

Summary

This study looks at whether aggressive weight loss using semaglutide can improve symptoms in people with a specific type of heart failure linked to obesity. About 81 participants with a BMI of 30 or higher will receive either semaglutide or a placebo. The main goal is to measure changes in heart pressure during exercise.

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Contacts and locations

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.