New drug cocktail aims to shrink melanoma before surgery
NCT ID NCT07586904
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether a combination of two drugs—cadonilimab and a high-dose interferon—can safely shrink tumors in people with stage III or IV melanoma before they have surgery. Ten participants will receive the drugs for three months, and researchers will monitor tumor response and side effects. The goal is to gather initial data to support larger future studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Cadonilimab and recombinant human interferon α1b
- What this could lead to
- If successful, this could point toward a new pre-surgery treatment option for advanced melanoma that helps shrink tumors before surgery.
- What could go wrong
- This is a very early, small trial with only 10 participants, so results may not apply to everyone. The drug combination may cause side effects like fatigue or immune reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xijing Hospital, Air Force Medical University Xi'an, Shaanxi, China
RECRUITINGXi'an, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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