New combo tackles tough pancreatic cancer

NCT ID NCT05052723

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tested two drugs, cabozantinib and pembrolizumab, in 21 people with metastatic pancreatic cancer that had worsened after standard treatment. The goal was to see if the combination could slow cancer growth. The study is complete, and results may help guide future research.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
cabozantinib and pembrolizumab
What this could lead to
If successful, this combination could offer a new treatment option for people with advanced pancreatic cancer that has not responded to standard therapies.
What could go wrong
This is a small, early-phase trial with only 21 participants, so results may not apply to everyone. The drugs can cause side effects, and the cancer may still progress.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kentucky Markey Cancer Center

    Lexington, Kentucky, 40536, United States

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