Could CAR t cells calm scleroderma? new trial launches.
NCT ID NCT06328777
First seen Sep 30, 2025 · Last updated May 01, 2026 · Updated 19 times
Summary
This early-phase trial tests a treatment called CABA-201, which uses a patient's own immune cells (CAR T cells) to target and destroy certain immune cells that may drive systemic sclerosis (scleroderma). The study aims to see if this approach is safe and can reduce disease activity in 12 adults with early, active disease affecting the skin, lungs, kidneys, or heart. Participants will be followed for side effects and changes in their condition.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 55905, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Northwestern Memorial Hospital
RECRUITINGChicago, Illinois, 60611, United States
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The University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale University
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact
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Conditions
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