New blood test could help patients who Don't respond to platelet transfusions
NCT ID NCT02858323
First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This study looked at 68 people with low platelet counts who had become resistant to platelet transfusions due to HLA antibodies. Researchers tested a new lab method (C1q binding) on stored blood samples to see if it could better predict whether a transfusion would work compared to the standard test. The goal was to improve matching for future transfusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If the C1q method proves more accurate, it could help doctors choose better platelet donors for patients who don't respond to standard transfusions.
What could go wrong
This is a small, completed observational study using stored samples, not a treatment trial. The new test may not be more useful than the current method in real-world settings.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States