New cocktail targets tough lymphoma: carfilzomib joins R-ICE in early trial

NCT ID NCT01959698

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested adding carfilzomib to a standard chemotherapy regimen (R-ICE) for adults with diffuse large B-cell lymphoma that returned or didn't respond to prior treatment. The main goals were to find the safest dose of carfilzomib and see how well the combination works. 29 participants were enrolled. The study is active but no longer recruiting.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States