New hope for tough lymphoma: drug combo shows promise in early trial

NCT ID NCT01959698

First seen Jan 30, 2026 · Last updated Apr 30, 2026 · Updated 10 times

Summary

This early-phase study tested a new combination of drugs (carfilzomib plus standard chemotherapy) in 29 adults with diffuse large B-cell lymphoma that had come back or not responded to prior treatment. The main goals were to find the safest dose of carfilzomib and see how well the combo works at shrinking tumors. While the approach aims to control the disease, it is not a cure, and ongoing management may still be needed.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

Conditions

Explore the condition pages connected to this study.