New drug combo aims to free hepatitis b patients from daily pills

NCT ID NCT07135349

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests whether a new injection called BW-20507, combined with pegylated interferon alfa, can help people with chronic hepatitis B stop their daily antiviral medication (NUCs). About 209 adults with hepatitis B will receive the combination for 48 weeks. The main goal is to see how many can safely stop NUCs by week 72.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BW-20507 injection combined with pegylated interferon alfa

What this could lead to

If successful, this combination could help some patients with chronic hepatitis B stop taking daily antiviral pills (NUCs) while keeping the virus under control.

What could go wrong

This is an early-phase (Phase 2) trial with only 209 participants, so results may not apply to all patients. The treatment involves injections over 48 weeks and may cause side effects like flu-like symptoms from interferon.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Argo Investigative Site

    Hefei, Anhui, 230022, China

  • Argo Investigative Site

    Beijing, Beijing Municipality, 100015, China

  • Argo Investigative Site

    Sichuan, Chengdu, China

  • Argo Investigative Site

    Chongqing, Chongqing Municipality, 400000, China

  • Argo Investigative Site

    Chongqing, Chongqing Municipality, China

  • Argo Investigative Site

    Fuzhou, Fujian, 350000, China

  • Argo Investigative Site

    Guangzhou, Guangdong, 510515, China

  • Argo Investigative Site

    Shenzhen, Guangdong, 518000, China

  • Argo Investigative Site

    Zunyi, Guizhou, 563000, China

  • Argo Investigative Site

    Changzhou, Jiangsu, 213000, China

  • Argo Investigative Site

    Xuzhou, Jiangsu, 22100, China

  • Argo Investigative Site

    Nanchang, Jiangxi, 330000, China

  • Argo Investigative Site

    Jiangxi, Nanchang, China

  • Argo Investigative Site

    Shanghai, Shanghai Municipality, 2000001, China

  • Argo Investigative Site

    Chengdu, Sichaun, 610041, China

  • Argo Investigative Site

    Chengdu, Sichuan, 610041, China

  • Argo Investigative Site

    Zhejiang, Wenzhou, China

  • Argo Investigative Site

    Hangzhou, Zhejiang, 310000, China